The University of Massachusetts Amherst

Search Results - alfred+crosby

3 Results Sort By:
Highly Resilient Synthetic Hydrogels with Tunable Mechanical Properties
This technology, developed by a team of polymer scientists at the University of Massachusetts Amherst, provides a versatile and simple method for producing highly resilient synthetic hydrogels with excellent mechanical properties comparable to the most efficient, naturally occurring elastic protein called resilin. The method involves the use of photo-initiated crosslinking reaction of hydrophilic and hydrophobic polymers having reactive end-groups in the presence of a tetra-functional thiol cross-linker. The resultant resilient hydrogels possess network elements of resilin, including a uniform network structure, low crosslink density, and an absence of secondary structures within the crosslinked primary chains. These hydrogels are capable of undergoing significant reversible deformation without energy loss (?97% resilience) at varying water content and show negligible hysteresis across a broad range of strains up to 300%. The swelling capacity, stiffness and fracture toughness of the hydrogels can be easily tuned by controlling the volume fractions of the hydrophilic and hydrophobic polymers to tailor the hydrogels to the specific needs of end-use applications. Current studies have focused on material elements common in extended wear contact lenses.
Published: 8/3/2023   |   Inventor(s): Gregory Tew, Melissa Lackey, Jun Cui, Catherine Walker, Alfred Crosby
Category(s): Material science, Healthcare
Reduced-Pain Syringe Needle Injection Systems
This invention provides cost-effective and user-friendly syringe needle injection systems that ease patients' discomfort during the injection operations.
Published: 8/10/2023   |   Inventor(s): Alfred Crosby, Shruti Rattan
Category(s): Healthcare, Devices
TUNABLE SURFACE WRINKLES FOR SMART ADHESION
This invention provides a novel, reusable adhesive surface with a well-defined surface wrinkle pattern as well as a facile, scalable and economical method to directly fabricate a patterned adhesive using a bottom-up approach. The patterning process involves swelling a laterally confined polymer film to develop surface wrinkles and photopolymerizing the swelling agent to stabilize the wrinkles. The control of adhesion is determined by the wavelength of the surface wrinkles, which is directly proportional to the thickness of the polymer film. Various processing parameters such as the film thickness, the polymer or swelling agent material, and the degree of lateral confinement can be adjusted to tune and control adhesion to produce truly "smart" adhesives for a variety of commercial applications.
Published: 8/3/2023   |   Inventor(s): Alfred Crosby, Edwin Chan, Ryan Hayward
Category(s): Material science, Engineering, Physical Science