The University of Massachusetts Amherst

Miniaturized, Cost-Effective Biosensing Devices for Point-of-Care and Therapeutic Screening Applications

LEAD INVENTOR:
Guangyu Xu, Ph.D.
 
PRODUCT OPPORTUNITIES

•       Miniaturized point-of-care (POC) cytokine sensing devices

•       Miniaturized point-of-care (POC) devices for rapid and real-time detection of biomarkers

•       Spectrally-filtered photodiode pairs for ratiometric sensing of biomolecules

•       Miniaturized biosensing devices for therapeutic screening applications

 
ADVANTAGES

•       Miniaturized, portable and wearable

•       High-precision lab-on-a chip biosensing devices

•       Rapid detection of biomolecules (e.g. cytokines)

•       High detection specificity and sensitivity

•       Does not require covalent labeling of the biomolecules to be detected

•       Cost-effective

•       Can be used for real-time and continuous monitoring of biomarkers (e.g. immune response monitoring)

•       Capable of multiplexed on-chip detection of biomolecules

 
TECHNOLOGY DESCRIPTION
This invention provides miniaturized and portable biosensing devices that employ novel spectrally-filtered photodiode pairs and on-chip ratiometric sensing. The biosensing devices allow for rapid, high-precision detection of biomolecules of interest, and can be used for point-of-care and therapeutic screening applications.
ABOUT THE LEAD INVENTOR
Dr. Guangyu Xu is the Linda and Dev Gupta Endowed Assistant Professor in the Department of Electrical and Computer Engineering at UMass Amherst. Dr. Xu's research groups aims to advance integrated molecular detection and multiplexed cell imaging tools for clinical applications, such as analytical genomics, cancer diagnosis, neurobiology, and self-powered implants.
AVAILABILITY:
Available for Licensing and/or Sponsored Research
DOCKET:
UMA 21-025
PATENT STATUS:
Patent Pending
Contact:
X. Helen Ma
Licensing Officer
University of Massachusetts
413-577-3750
hma@research.umass.edu
Inventor(s):
Guangyu Xu
Keywords: