Miniaturized, Cost-Effective Biosensing Devices for Point-of-Care and Therapeutic Screening Applications
Guangyu Xu, Ph.D.
• Miniaturized point-of-care (POC) cytokine sensing devices • Miniaturized point-of-care (POC) devices for rapid and real-time detection of biomarkers • Spectrally-filtered photodiode pairs for ratiometric sensing of biomolecules • Miniaturized biosensing devices for therapeutic screening applications
• Miniaturized, portable and wearable • High-precision lab-on-a chip biosensing devices • Rapid detection of biomolecules (e.g. cytokines) • High detection specificity and sensitivity • Does not require covalent labeling of the biomolecules to be detected • Cost-effective • Can be used for real-time and continuous monitoring of biomarkers (e.g. immune response monitoring) • Capable of multiplexed on-chip detection of biomolecules
This invention provides miniaturized and portable biosensing devices that employ novel spectrally-filtered photodiode pairs and on-chip ratiometric sensing. The biosensing devices allow for rapid, high-precision detection of biomolecules of interest, and can be used for point-of-care and therapeutic screening applications.
Dr. Guangyu Xu is the Linda and Dev Gupta Endowed Assistant Professor in the Department of Electrical and Computer Engineering at UMass Amherst. Dr. Xu's research groups aims to advance integrated molecular detection and multiplexed cell imaging tools for clinical applications, such as analytical genomics, cancer diagnosis, neurobiology, and self-powered implants.
Available for Licensing and/or Sponsored Research
UMA 21-025
Patent Pending
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