Novel Chemical Reagents for Antibody-Drug Conjugation, Protein Delivery, and Traceless Release
S. Thai Thayumanavan, Ph.D.
- Novel chemical reagents for antibody-drug conjugation, protein delivery, and traceless release
- Antibody-drug conjugates with reversible linker
- Novel chemical reagent-functionalized polymeric delivery vehicles for protein delivery and traceless release
- Reversible bonding reaction with small molecule or protein therapeutics
- Versatile linker for antibody-drug conjugation
- Responsive to intracellular conditions for traceless release of therapeutics
This invention provides a new class of chemical reagents that can function as a versatile molecular switch to allow for the bonding and debonding of small molecule or protein therapeutics for targeted and efficient delivery and traceless release.
Dr. Thayumanavan is a Professor in the Department of Chemistry. He is a highly accomplished expert in organic and polymer chemistry and a prolific inventor. His research focuses on the design, synthesis and characterization of organic macromolecules of interest in supramolecular chemistry, materials science and biological applications. Dr. Thayumanavan has broad and well-established expertise in developing custom-designed molecules for specific end-use applications such as pharmaceutical delivery, smart sensors, and fuel cells.
Available for Licensing and/or Sponsored Research
UMA 18-054
Patent Pending
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