New Protein Labeling Reagents for Improved Protein Structural Analysis by Mass Spectrometry
Richard Vachet, Ph.D.
- New protein labeling reagents for improved protein structural analysis by mass spectrometry
- Capable of reacting with a wider range of surface-exposed amino acid residues in proteins, leading to greater structural coverage as compared with commonly used protein labeling reagents for mass spectrometric analysis.
- Higher sensitivity of comparative protein structural characterization
- Tunable reactivity by incorporating desired functional groups
This invention provides new chemical reagents that can react with a wide range of amino acid residues on proteins, allowing improved comparative protein structural analysis by mass spectrometry.
Dr. Vachet is a Professor in the Department of Chemistry at UMass Amherst. His reserach group focuses on developing measurement tools to help optimize drug delivery and to assess the effectiveness of the delivered therapeutics.
Available for Licensing and/or Sponsored Research
UMA 18-055
Patent Pending
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