The University of Massachusetts Amherst

Search Results - Research+tools

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Magnetohydrodynamic clearing and antibody staining
Published: 5/3/2024   |   Inventor(s): Joseph Bergan, Joseph Dwyer
Category(s): Biotechnology, Devices, Life Sciences, Research tools
Let-7 promotes superior anti-tumor activity of CD8 T cells and memory formation
Published: 4/29/2024   |   Inventor(s): Leonid Pobezinsky, Elena Pobezinskaya
Category(s): Biotechnology, Life Sciences, Therapeutics & prevention, Research tools
Microfluidic Devices with Graphene Electrodes
Published: 3/1/2024   |   Inventor(s): Sarah Perry, Shuo Sui
Category(s): Devices, Engineering, Material science, Research tools
Flow Sensor Based on Coulometric Interrogation of a Graphene Microelectrode
Published: 3/1/2024   |   Inventor(s): Jinglei Ping, Xiaoyu Zhang
Category(s): Devices & sensors, Engineering, Healthcare, Life Sciences, Research tools, Electronics
Katsumata / Vinyl-Comonomer Additive for Radically Activated Dynamic Phenomena
Published: 2/8/2024   |   Inventor(s): Reika Katsumata, Autumn Mineo
Category(s): Chemicals, Engineering, Material science, Physical Science, Research tools
Nanopore Tweezer System for Protein Kinase Allosteric Drug Screening
Protein kinases are enzymes that catalyze the phosphorylation of substrate proteins, regulating a wide range of cellular pathways. Aberrant kinase activities are implicated in various human diseases, making the kinases essential drug targets. This invention provides a nanopore-tweezer-based compound screening platform for the identification of allosteric drugs that can bind to allosteric sites on protein kinases and overcome drug resistance.
Published: 8/3/2023   |   Inventor(s): Min Chen, Fanjun Li
Category(s): Biotechnology, Life Sciences, Research tools
Cell-Membrane-Coated Polymeric Nanoparticles for Selective Intracellular Delivery of Therapeutics
Published: 8/10/2023   |   Inventor(s): Sankaran Thayumanavan
Category(s): Healthcare, Life Sciences, Biotechnology, Nanotechnology, Therapeutics & prevention, Research tools
Nanopore-based Sensors for Antibody Screening Applications
This invention provides OmpG nanopore-based sensors for antibody screening applications. Each OmpG nanopore is engineered to contain a heterologous peptide sequence in one or more flexible loops of the nanopore, allowing for target-specific binding and detection.
Published: 6/26/2023   |   Inventor(s): Min Chen, Joshua Foster, Minji Kim, Matthew Moore
Category(s): Devices & sensors, Life Sciences, Research tools
Novel Ferroptosis Inducing Compounds as Anti-cancer Agents
Ferroptosis is a well-defined cell death mechanism distinct from other regulated cell death phenotypes such as apoptosis, necrosis and autophagy. This invention provides novel ferroptosis inducer compounds that represent a new class of highly specific chemotherapeutic agents.
Published: 8/10/2023   |   Inventor(s): Rachid Skouta, Thomas Dawson, Rohit Bhadoria
Category(s): Chemicals, Healthcare, Life Sciences, Research tools, Therapeutics & prevention
Demineralized Bone Paper and Applications Thereof
This invention provides structurally well-defined, three-dimensional bone tissue grafts produced from stacked demineralized bone paper (DBP), methods for treating a subject using such bone tissue grafts, methods for making DBP, and in vitro assay systems and methods for assaying the effect of an agent on bone development or health.
Published: 8/10/2023   |   Inventor(s): Jungwoo Lee, Jae-Hyuck Shim, Ryan Carpenter, Yongkuk Park, Jun-Goo Kwak
Category(s): Biotechnology, Devices, Healthcare, Life Sciences, Research tools, Therapeutics & prevention
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