The University of Massachusetts Amherst

Cell-Membrane-Coated Polymeric Nanoparticles for Selective Intracellular Delivery of Therapeutics

LEAD INVENTOR:
S. Thai Thayumanavan, Ph.D.
 
PRODUCT OPPORTUNITIES

  • Cell-membrane-coated, cargo-encapsulated polymer nanoparticles as target-specific prodrugs

 
COMPETITIVE ADVANTAGES

  • Enhanced cellular uptake and endosomal escape, resulting in more efficient delivery of therapeutics
  • Enhanced selectivity of intracellular delivery of therapeutics

 
TECHNOLOGY DESCRIPTION
This invention provides cell-membrane-coated polymeric nanoparticles for efficient and selective intracellular delivery of therapeutics such as small molecule drugs, nucleic acids, and proteins.
ABOUT THE INVENTOR
Dr. Thayumanavan is a Distinguished Professor in the Department of Chemistry. He is a highly accomplished expert in organic and polymer chemistry and a prolific inventor. His research focuses on the design, synthesis and characterization of organic macromolecules of interest in supramolecular chemistry, materials science and biological applications. Dr. Thayumanavan has broad and well-established expertise in developing custom-designed molecules for specific end-use applications such as targeted delivery of therapeutics, smart sensors, and fuel cells.

AVAILABILITY:
Available for Licensing and/or Sponsored Research
DOCKET:
UMA 22-063
F
PATENT STATUS:
Patent Pending
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Contact:
Nikki Hoang
Licensing Officer
University of Massachusetts
nikkihoang@research.umass.edu
Inventor(s):
Sankaran Thayumanavan
Keywords: