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Search Results - Therapeutics+%26+prevention
22
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Localization of Payload Delivery Systems to Tumor Sites via Beacon Cell Targeting
[%SearchResultsTechnologyDescription%]
Published: 3/1/2024
|
Inventor(s):
Neil Forbes
,
Nele Van Dessel
,
John Klier
,
Shane Taylor
,
Vishnu Raman
Category(s):
Biotechnology
,
Healthcare
,
Life Sciences
,
Therapeutics & prevention
Noncationic Nucleic Acid-Polymer Complexes for Nucleic Acid Delivery
[%SearchResultsTechnologyDescription%]
Published: 10/26/2023
|
Inventor(s):
Sankaran Thayumanavan
Category(s):
Biotechnology
,
Healthcare
,
Nanotechnology
,
Life Sciences
,
Therapeutics & prevention
Cell-Membrane-Coated Polymeric Nanoparticles for Selective Intracellular Delivery of Therapeutics
[%SearchResultsTechnologyDescription%]
Published: 8/10/2023
|
Inventor(s):
Sankaran Thayumanavan
Category(s):
Healthcare
,
Life Sciences
,
Biotechnology
,
Nanotechnology
,
Therapeutics & prevention
,
Research tools
Novel Ferroptosis Inducing Compounds as Anti-cancer Agents
Ferroptosis is a well-defined cell death mechanism distinct from other regulated cell death phenotypes such as apoptosis, necrosis and autophagy. This invention provides novel ferroptosis inducer compounds that represent a new class of highly specific chemotherapeutic agents.
Published: 8/10/2023
|
Inventor(s):
Rachid Skouta
,
Thomas Dawson
,
Rohit Bhadoria
Category(s):
Chemicals
,
Healthcare
,
Life Sciences
,
Research tools
,
Therapeutics & prevention
Demineralized Bone Paper and Applications Thereof
This invention provides structurally well-defined, three-dimensional bone tissue grafts produced from stacked demineralized bone paper (DBP), methods for treating a subject using such bone tissue grafts, methods for making DBP, and in vitro assay systems and methods for assaying the effect of an agent on bone development or health.
Published: 8/10/2023
|
Inventor(s):
Jungwoo Lee
,
Jae-Hyuck Shim
,
Ryan Carpenter
,
Yongkuk Park
,
Jun-Goo Kwak
Category(s):
Biotechnology
,
Devices
,
Healthcare
,
Life Sciences
,
Research tools
,
Therapeutics & prevention
Polymeric Nanoparticle-Based Antibiofilm Therapy
This invention provides a novel therapeutic platform to combat multidrug-resistant bacterial and biofilm infections using engineered polymeric nanoparticles. The polymeric nanoparticles can penetrate and eradicate pre-formed bacterial biofilms while maintaining high therapeutic indices. The nanoparticles are formed via self-assembly of engineered synthetic polymers in aqueous solutions, without the need to use any organic solvent or purification procedures.
Published: 8/10/2023
|
Inventor(s):
Vincent Rotello
,
Ryan Landis
,
Akash Gupta
Category(s):
Healthcare
,
Life Sciences
,
Biotechnology
,
Therapeutics & prevention
An Ex Vivo Method of Generating Super Regulatory T Cells as a Cell-based Therapy for the Prevention of Graft-vs-Host Disease
Regulatory T cells maintain immunological tolerance and dampen inflammatory responses. Administering regulatory T cells can prevent the immune-mediated tissue destruction of graft-versus-host disease, which frequently accompanies hematopoietic stem cell transfer. This technology provides a simple and effective method to generate and expand a unique population of stable and highly suppressive regulatory T cells, which can be used as a cell-based therapy for the prevention of graft-versus-host disease.
Published: 10/3/2023
|
Inventor(s):
Lisa Minter
,
Gregory Tew
,
Emrah Ozay
Category(s):
Biotechnology
,
Healthcare
,
Life Sciences
,
Research tools
,
Therapeutics & prevention
Novel Small Molecule Inhibitors of Caspase-6
[%SearchResultsTechnologyDescription%]
Published: 8/10/2023
|
Inventor(s):
Jeanne Hardy
,
Penchala Narasimharao Meka
Category(s):
Therapeutics & prevention
,
Life Sciences
,
Healthcare
A Novel Non-cationic Lipid-polymer-based Nanossembly for the Complexation and Intracellular Delivery of Nucleic Acids
[%SearchResultsTechnologyDescription%]
Published: 10/3/2023
|
Inventor(s):
Sankaran Thayumanavan
,
Kingshuk Dutta
Category(s):
Biotechnology
,
Healthcare
,
Life Sciences
,
Nanotechnology
,
Therapeutics & prevention
Novel Polymeric Nanogels for Controlled Intracellular Protein Delivery and Traceless Release
[%SearchResultsTechnologyDescription%]
Published: 10/3/2023
|
Inventor(s):
Sankaran Thayumanavan
,
Jiaming Zhuang
Category(s):
Life Sciences
,
Biotechnology
,
Healthcare
,
Research tools
,
Therapeutics & prevention
,
Nanotechnology
,
Diagnostic technology
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