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Kulkarni/ Sprayable polymeric scaffold loaded with inflammasome-inhibiting lipid nanorods for anti-inflammatory therapy
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Reactive Particles for Cold Spray Coatings
This invention demonstrates solid or semi-solid microparticles that undergo crosslinking and polymerization upon contacting a substrate to form a coating. The microparticles are maintained in an un-reacted state until delivered using cold spray processes where they are propelled using a gas stream at a pre-determined temperature and velocity. The process does not require volatile organic solvents or aqueous vehicles, nor plural component spray or two component formulations with limited shelf life but still deliver uniform coating.
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Ultra-Stable Printing using Aqueous Complex Coacervates
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Noncationic Nucleic Acid-Polymer Complexes for Nucleic Acid Delivery
This invention provides a new strategy for nucleic acid delivery by using novel cross-linkable and surface-charge modifiable synthetic polymers. The use of the novel polymer system allows for robust nuclecid-polymer complexation, easy removal of cationic moieties of the polymer and self-crosslinking of the polymer in a single step, and stimuli-responsive release of the nucleic acid molecules in the cell.
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ARTIFICIAL NEURONS USING DIFFUSIVE MEMRISTOR
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Economical Surface Treatment for Harvesting Epithelial Cells from Biological Fluids
This invention provides economical, bio-interactive surfaces and surface treatment methods for selective capture of targeted epithelial cells or other cell types from cell mixtures or complex biological fluids. Preparation or fabrication of the engineered surfaces provided by this technology does not require the use of expensive and unstable biomolecular materials, and the resulting surfaces can distinguish different cell types or cells that express different levels of the same surface adhesion marker. Such engineered surfaces can be used as economical tools for assessment of cancer risk, cancer diagnosis, and tracking of the effectiveness of cancer treatments, among other potential applications.
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Stablizing Liquid Drops ofof Arbitrary Shapes by the Interfacial Jamming of Nanoparticles
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Geobacter Sulfurreducens Conductive Pili as Biological Nanowires and Uses Thereof
The present invention reports the conductive properties of Geobacter sulfurreducens pili (geopili) and their use in nanotechnology applications. More specifically the present invention provides methods for culturing cells of G. sulfurreducens to produce conductive pili, as well as methods for their isolation and for their modification in order to produce biological nanowires or biological/inorganic hybrid devices with different functionalities. The invention provides applications for cells expressing native or modified pili as well as for the isolated native or modified pili. |
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Polymeric Nanogles for the Encapsulation, Delivery and pH-Triggered Release of Proteins
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Rapid Detection of Penetration of Pesticides, Antibiotices or Other Analytes in Plants and Produce
This invention provides a simple and rapid method for measuring pesticide and/or antibiotic penetration into plants and produce. The method involves the use of surface-enhanced Raman scattering (SERS) mapping for in situ and real-time tracking of the analytes by using metallic nanoparticles as probes.
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