Novel Ferroptosis Inducing Compounds as Anti-cancer Agents
Rachid Skouta, Ph.D.
• Ferroptosis inducing compounds for anti-cancer therapy
• Ferroptosis inducers as research reagents
• Highly target-specific
• Can be used a complementary-mechanism-based therapy for front-line cancer treatments
• Can be used to target hard to treat cancers
Ferroptosis is a well-defined cell death mechanism distinct from other regulated cell death phenotypes such as apoptosis, necrosis and autophagy. This invention provides novel ferroptosis inducer compounds that represent a new class of highly specific chemotherapeutic agents.
Dr. Rachid Skouta's research interests at the University of Massachusetts Amherst include designing and developing small molecule drugs with specific predicted properties via structure-activity-relationship (SAR) studies to target receptor, transporters and enzymes involved in neurodegenerative, cancer and infectious disease models.
Available for Licensing and/or Sponsored Research
UMA 20-041
F
Patent Pending
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