The University of Massachusetts Amherst

Search Results - Nanotechnology

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Reactive Particles for Cold Spray Coatings
This invention demonstrates solid or semi-solid microparticles that undergo crosslinking and polymerization upon contacting a substrate to form a coating. The microparticles are maintained in an un-reacted state until delivered using cold spray processes where they are propelled using a gas stream at a pre-determined temperature and velocity. The process does not require volatile organic solvents or aqueous vehicles, nor plural component spray or two component formulations with limited shelf life but still deliver uniform coating.
Published: 11/18/2024   |   Inventor(s): Jessica Schiffman, Victor Champagne, John Klier, Guozhen Yang, Mengfei Huang
Category(s): Chemicals, Engineering, Material science, Nanotechnology
Ultra-Stable Printing using Aqueous Complex Coacervates
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Published: 11/5/2024   |   Inventor(s): Jessica Schiffman, Sarah Perry, Xiangxi Meng
Category(s): Material science, Nanotechnology, Chemicals, Engineering
Noncationic Nucleic Acid-Polymer Complexes for Nucleic Acid Delivery
This invention provides a new strategy for nucleic acid delivery by using novel cross-linkable and surface-charge modifiable synthetic polymers. The use of the novel polymer system allows for robust nuclecid-polymer complexation, easy removal of cationic moieties of the polymer and self-crosslinking of the polymer in a single step, and stimuli-responsive release of the nucleic acid molecules in the cell.
Published: 11/29/2024   |   Inventor(s): Sankaran Thayumanavan
Category(s): Biotechnology, Healthcare, Nanotechnology, Life Sciences, Therapeutics & prevention
ARTIFICIAL NEURONS USING DIFFUSIVE MEMRISTOR
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Published: 6/26/2023   |   Inventor(s): Jianhua (joshua) Yang, Qiangfei Xia, Mark McLean, Qing Wu
Category(s): Devices, Computers, Communications & internet, Devices & sensors, Electronics, Engineering, Nanotechnology
Economical Surface Treatment for Harvesting Epithelial Cells from Biological Fluids
This invention provides economical, bio-interactive surfaces and surface treatment methods for selective capture of targeted epithelial cells or other cell types from cell mixtures or complex biological fluids. Preparation or fabrication of the engineered surfaces provided by this technology does not require the use of expensive and unstable biomolecular materials, and the resulting surfaces can distinguish different cell types or cells that express different levels of the same surface adhesion marker. Such engineered surfaces can be used as economical tools for assessment of cancer risk, cancer diagnosis, and tracking of the effectiveness of cancer treatments, among other potential applications.
Published: 8/4/2025   |   Inventor(s): Maria Santore, Kathleen Arcaro, Surachate Kalasin
Category(s): Biotechnology, Nanotechnology, Diagnostic technology, Devices & sensors, Life Sciences, Healthcare, Research tools
Stablizing Liquid Drops ofof Arbitrary Shapes by the Interfacial Jamming of Nanoparticles
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Published: 8/10/2023   |   Inventor(s): Thomas Russell, Todd Emrick, Mengmeng Cui
Category(s): Material science, Nanotechnology, Engineering, Physical Science
Geobacter Sulfurreducens Conductive Pili as Biological Nanowires and Uses Thereof

The present invention reports the conductive properties of Geobacter sulfurreducens pili (geopili) and their use in nanotechnology applications. More specifically the present invention provides methods for culturing cells of G. sulfurreducens to produce conductive pili, as well as methods for their isolation and for their modification in order to produce biological nanowires or biological/inorganic hybrid devices with different functionalities.  The invention provides applications for cells expressing native or modified pili as well as for the isolated native or modified pili.

Published: 12/9/2022   |   Inventor(s): Derek Lovley, Gemma Reguera, Kevin McCarthy, Mark Thomas Tuominen
Category(s): Life Sciences, Environmental, Nanotechnology, Biotechnology
Polymeric Nanogles for the Encapsulation, Delivery and pH-Triggered Release of Proteins
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Published: 8/10/2023   |   Inventor(s): Sankaran Thayumanavan, Mijanur Molla, Scott Garman
Category(s): Biotechnology, Diagnostic technology, Healthcare, Life Sciences, Nanotechnology, Research tools
Rapid Detection of Penetration of Pesticides, Antibiotices or Other Analytes in Plants and Produce
This invention provides a simple and rapid method for measuring pesticide and/or antibiotic penetration into plants and produce. The method involves the use of surface-enhanced Raman scattering (SERS) mapping for in situ and real-time tracking of the analytes by using metallic nanoparticles as probes.
Published: 8/10/2023   |   Inventor(s): Lili He
Category(s): Environmental, Food technology & plant science, Nanotechnology, Research tools
Hierarchically Ordered Nanoscale Electric Field Concentrators for Embedded Thin Film Devices
Resistance switching devices, also known as memristive devices, represent the next generation in computing. With a typical metal-oxide-metal structure, memristors change resistance under different external biases and retain this new resistance even when power is turned off. This allows memristors to store data without needing constant power like in traditional computer memory. Memristors have other desirable properties such as low power consumption, fast switching speed, and multistate logic potential. These properties open up next generation computing applications in non-volatile memory, reconfigurable switches, bio-inspired neuromorphic computing, and radiofrequency switches. However, before these applications are enabled, significant technical challenges in memristors must be overcome. These include cycle-to-cycle instabilities in operating voltage and resistance states, which cause memory retention and device endurance issues.

 

Professor Stephen Nonnenmann and his laboratory address these instability issues by embedding highly ordered metal nanoislands in the memristor’s oxide switching layer. Through a unique template-directed nanoisland embedding procedure, the nanoisland diameter, spacing, and area density can be precisely controlled. The Nonnenmann lab found that through precise control of these variables, the growth of conductive filaments formed through the memristor’s oxide layer, which enable its unique properties, can be more precisely controlled, leading to a nearly 100% improvement in uniformity performance in one device case.

Published: 6/26/2023   |   Inventor(s): Stephen Nonnenmann, Jiaying Wang
Category(s): Computers, Electronics, Engineering, Nanotechnology, Material science, Devices & sensors
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