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Novel Polymeric Nanogels for Controlled Intracellular Protein Delivery and Traceless Release
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Published: 9/13/2019   |   Inventor(s): Sankaran Thayumanavan, Jiaming Zhuang
Category(s): Life Sciences, Biotechnology, Healthcare, Research tools, Therapeutics & prevention, Nanotechnology, Diagnostic technology
Economical Surface Treatment for Harvesting Epithelial Cells from Biological Fluids
This invention provides economical, bio-interactive surfaces and surface treatment methods for selective capture of targeted epithelial cells or other cell types from cell mixtures or complex biological fluids. Preparation or fabrication of the engineered surfaces provided by this technology does not require the use of expensive and unstable biomolecular materials, and the resulting surfaces can distinguish different cell types or cells that express different levels of the same surface adhesion marker. Such engineered surfaces can be used as economical tools for assessment of cancer risk, cancer diagnosis, and tracking of the effectiveness of cancer treatments, among other potential applications.
Published: 9/13/2019   |   Inventor(s): Maria Santore, Kathleen Arcaro, Surachate Kalasin
Category(s): Biotechnology, Nanotechnology, Diagnostic technology, Devices & sensors, Life Sciences, Healthcare, Research tools
Organic Photovoltaic Devices Based on Water-based Nanoparticle Dispersions
This invention provides organic photovoltaic devices fabricated using an environmentally friendly fabrication process. To fabricate a solar cell that will power a smart phone using conventional fabrication processes would require 150 milliliter of toxic organic solvents such as chlorobenzene or xylene. The new fabrication process of this invention uses water-based nanoparticle dispersions of active layer materials, and improves device power conversion efficiency over other aqueous- dispersion-based processes by optimizing the domain size and structure of the active layer and other device elements.

Published: 9/13/2019   |   Inventor(s): Dhandapani Venkataraman, Monojit Bag, Timothy Gehan, Christie Cutting
Category(s): Devices, Engineering, Nanotechnology, Physical Science, Clean Energy
Stablizing Liquid Drops ofof Arbitrary Shapes by the Interfacial Jamming of Nanoparticles
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Published: 9/13/2019   |   Inventor(s): Thomas Russell, Todd Emrick, Mengmeng Cui
Category(s): Material science, Nanotechnology, Engineering, Physical Science
Hyaluronic Acid Based Nanogel or Microgel Compositions for Targeted Delivery of Small Molecule Therapeutics
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Published: 9/13/2019   |   Inventor(s): Sankaran Thayumanavan, Lisa Minter
Category(s): Biotechnology, Diagnostic technology, Healthcare, Life Sciences, Nanotechnology, Research tools, Therapeutics & prevention
Hierarchically Ordered Nanoscale Electric Field Concentrators for Embedded Thin Film Devices
Resistance switching devices, also known as memristive devices, represent the next generation in computing. With a typical metal-oxide-metal structure, memristors change resistance under different external biases and retain this new resistance even when power is turned off. This allows memristors to store data without needing constant power like in traditional computer memory. Memristors have other desirable properties such as low power consumption, fast switching speed, and multistate logic potential. These properties open up next generation computing applications in non-volatile memory, reconfigurable switches, bio-inspired neuromorphic computing, and radiofrequency switches. However, before these applications are enabled, significant technical challenges in memristors must be overcome. These include cycle-to-cycle instabilities in operating voltage and resistance states, which cause memory retention and device endurance issues.

 

Professor Stephen Nonnenmann and his laboratory address these instability issues by embedding highly ordered metal nanoislands in the memristor’s oxide switching layer. Through a unique template-directed nanoisland embedding procedure, the nanoisland diameter, spacing, and area density can be precisely controlled. The Nonnenmann lab found that through precise control of these variables, the growth of conductive filaments formed through the memristor’s oxide layer, which enable its unique properties, can be more precisely controlled, leading to a nearly 100% improvement in uniformity performance in one device case.

Published: 5/20/2019   |   Inventor(s): Stephen Nonnenmann, Jiaying Wang
Category(s): Computers, Electronics, Engineering, Nanotechnology, Material science, Devices & sensors
Nanopatterned Articles Produced Using Reconstructed Block Copolymer Films
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Published: 2/26/2019   |   Inventor(s): Thomas Russell, Soojin Park, Jia-Yu Wang, Bokyung Kim
Category(s): Material science, Nanotechnology, Devices, Engineering, Computers
A Simple, Scalable Method for Producing Bicontinuous Jammed Emulsions (or Bijels) with Sub-micrometer Domains
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Published: 9/14/2018   |   Inventor(s): Thomas Russell, Caili Huang, Joseph Forth, Brett Helms
Category(s): Physical Science, Nanotechnology, Material science
Sub-5 nm Full Pitch Lamellar Microdomains by Chemical Transformation
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Published: 8/24/2018   |   Inventor(s): Thomas Russell, Duk Man Yu, Javid Rzayev, Jose Kenneth Mapas
Category(s): Material science, Nanotechnology, Physical Science
Direct Printing of 3-D Microbatteries and High Surface-Area Electrodes
This invention provides highly scalable methods to fabricate 3-D lithium ion microbatteries and high surface-area electrodes for microbatteries. The methods involve imprint patterning nanoparticle-based inks using nanoimprint lithography to form high surface-area electrodes and 3-D microbatteries with well-engineered architectures. The 3-D microbatteries offer superior performance with greatly enhanced capacity and power, and can be rapidly charged and discharged.
Published: 8/22/2018   |   Inventor(s): James Watkins, Wenhao Li
Category(s): Material science, Nanotechnology, Physical Science
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