Nanoparticle-Stabilized Microcapsules for Effective Treatment of Bacterial Biofilms

•       Antimicrobial ointments and creams for treatments of infected wounds

•       Antimicrobial toothpaste, mouthwash and dental floss

•       Disinfectants for biomedical surfaces

•       Stable and biocompatible microcapsules

•       Highly potent in biofilm inhibition and eradication

•       Spontaneous assembly of microcapsules

Bacterial biofilms are widely associated with persistent infections. The amphiphilic construct of biofilms provides protection for bacterial cells by reducing absorption of conventional antimicrobials. This invention provides new nanoparticle-stabilized antimicrobial microcapsules that can effectively inhibit and eradicate pathogenic biofilms. The microcapsules contain antimicrobial essential oil materials and can efficiently deliver such materials to the cells of pathogenic bacteria in the biofilm, resulting in effective killing of the bacteria.