The University of Massachusetts Amherst

Nanoparticle-Stabilized Microcapsules for Effective Treatment of Bacterial Biofilms

LEAD INVENTOR:
Vincent M. Rotello, Ph.D.
 
PRODUCT OPPORTUNITIES

•       Antimicrobial ointments and creams for treatments of infected wounds

•       Antimicrobial toothpaste, mouthwash and dental floss

•       Disinfectants for biomedical surfaces

 
ADVANTAGES

•       Stable and biocompatible microcapsules

•       Highly potent in biofilm inhibition and eradication

•       Spontaneous assembly of microcapsules

 
TECHNOLOGY DESCRIPTION

Bacterial biofilms are widely associated with persistent infections. The amphiphilic construct of biofilms provides protection for bacterial cells by reducing absorption of conventional antimicrobials. This invention provides new nanoparticle-stabilized antimicrobial microcapsules that can effectively inhibit and eradicate pathogenic biofilms. The microcapsules contain antimicrobial essential oil materials and can efficiently deliver such materials to the cells of pathogenic bacteria in the biofilm, resulting in effective killing of the bacteria.

ABOUT THE LEAD INVENTOR

Dr. Vincent M. Rotello is the Charles A. Goessmann Professor of Chemistry at the University of Massachusetts Amherst. His research team focuses on creating new functional materials for a variety of applications.
AVAILABILITY:
Available for Licensing and/or Sponsored Research
DOCKET:
UMA 16-009
F
PATENT STATUS:
US Patent US 10,272126 issued
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Contact:
Nikki Hoang
Licensing Officer
University of Massachusetts
nikkihoang@research.umass.edu
Inventor(s):
Vincent Rotello
Bradley Duncan
Xiaoning A/k/a Sharlene Li
Keywords: