The University of Massachusetts Amherst

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Stable, Biocompatible and “Green” Protein Films for Antifouling, Antimicrobial and Tissue Engineering Applications
This invention provides protein films or coatings for antifouling, antimicrobial and tissue engineering applications, and scalable, environment-friendly methods for fabricating the films. The films are water-stable, biocompatible and resistant to protein and bacterial fouling, and can be made to direct human cell adhesion, alignment and growth. The films can be fabricated on both hard and flexible substrates, and the fabrication process does not involve the use of environmentally hazardous materials such as organic solvents or chemical crossslinkers. The biodegradability of the films can be tuned to enable controlled release of functional or therapeutic agents.
Published: 8/10/2023   |   Inventor(s): Vincent Rotello, Bradley Duncan, Li-Sheng Wang, Eunhee Jeoung, Chandramouleeswaran Subramani, Krishnendu Saha
Category(s): Biotechnology, Environmental, Engineering, Healthcare, Life Sciences