A Simple Method for Making Biocompatible Protein Films as Antimicrobial Coatings
This invention provides a simple method for making protein films or coatings for antifouling, antimicrobial, and tissue engineering applications. The films are water-stable, biocompatible and resistant to protein and bacterial fouling. The films can be fabricated on substrates with simple or complex geometries. The biodegradability of the films can be tuned to enable controlled release of functional or therapeutic agents.
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Stable, Biocompatible and “Green” Protein Films for Antifouling, Antimicrobial and Tissue Engineering Applications
This invention provides protein films or coatings for antifouling, antimicrobial and tissue engineering applications, and scalable, environment-friendly methods for fabricating the films. The films are water-stable, biocompatible and resistant to protein and bacterial fouling, and can be made to direct human cell adhesion, alignment and growth. The films can be fabricated on both hard and flexible substrates, and the fabrication process does not involve the use of environmentally hazardous materials such as organic solvents or chemical crossslinkers. The biodegradability of the films can be tuned to enable controlled release of functional or therapeutic agents.
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