The University of Massachusetts Amherst

Hyaluronic Acid Based Nanogel or Microgel Compositions for Targeted Delivery of Small Molecule Therapeutics

LEAD INVENTOR:
S. Thai Thayumanavan, Ph.D.
 
PRODUCT OPPORTUNITIES

  • Crosslinked hyaluronic acid - small molecule nano- or micro-assemblies as therapeutics for immune-mediated inflammatory diseases
  • Crosslinked hyaluronic acid - small molecule nano- or micro-assemblies as therapeutics for caner
  • Crosslinked hyaluronic acid - small molecule nano- or micro-assemblies as diagnostic agents
  • Crosslinked hyaluronic acid - small molecule nano- or micro-assemblies as intracellular imaging agents

 
COMPETITIVE ADVANTAGES

  • High drug (or small molecule) loading capacity
  • Cell-type-specific targeting and drug (or small molecule) release
  • Novel nanogel/microgel compositions
  • Novel prodrug compositions

 
TECHNOLOGY DESCRIPTION
This invention provides novel compositions of crosslinked hyaluronic acid - small molecule nano- or micro-assemblies as therapeutics for immune-medicated diseases or cancer, or as diagnostic or imaging agents.
ABOUT THE INVENTOR
Dr. Thayumanavan is a Professor in the Department of Chemistry. He is a highly accomplished expert in organic and polymer chemistry and a prolific inventor. His research focuses on the design, synthesis and characterization of organic macromolecules of interest in supramolecular chemistry, materials science and biological applications. Dr. Thayumanavan has broad and well-established expertise in developing custom-designed molecules for specific end-use applications such as pharmaceutical delivery, smart sensors, and fuel cells.

AVAILABILITY:
Available for Licensing and/or Sponsored Research
DOCKET:
UMA 17-047
PATENT STATUS:
Patent Pending
Contact:
Nikki Hoang
Licensing Officer
University of Massachusetts
nikkihoang@research.umass.edu
Inventor(s):
Sankaran Thayumanavan
Lisa Minter
Keywords: